FOXO3 anticorps

N° du produit ABIN966151

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO3 dans IHC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 4+ publications.

Aperçu rapide pour FOXO3 anticorps (ABIN966151)

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FOXO3 anticorps

Specificité: FKHRL1 (Ab-253) antibody detects endogenous levels of total FKHR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR1 around the phosphorylation site of serine 253.

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-FOXO3 (ABIN966151)

Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." dans: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, (2005) (PubMed).

Essafi, Fernández de Mattos, Hassen, Soeiro, Mufti, Thomas, Medema, Lam: "Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells." dans: Oncogene, Vol. 24, Issue 14, pp. 2317-29, (2005) (PubMed).

Brunet, Park, Tran, Hu, Hemmings, Greenberg: "Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)." dans: Molecular and cellular biology, Vol. 21, Issue 3, pp. 952-65, (2001) (PubMed).

Goode, Grauer, Gums: "Infectious vaginitis. Selecting therapy and preventing recurrence." dans: Postgraduate medicine, Vol. 96, Issue 6, pp. 85-8, 91-8, (1994) (PubMed).

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FKHRL1

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis